Paul Alivisatos, Berkeley Lab director and UC Berkeley professor, has won the prestigious Wolf Foundation Prize in Chemistry for 2012. Alivisatos is an internationally recognized authority on nanochemistry and a pioneer in the synthesis of semiconductor quantum dots and multi-shaped artificial nanostructures. He shares this year’s Wolf Prize in Chemistry with fellow nanoscience expert Charles Lieber of Harvard University.

Berkeley Lab scientists and their colleagues in the Sloan Digital Sky Survey have used visual data from nearly a million galaxies to derive the most accurate calculation yet of how matter clumps together – from a time when the universe was only half its present age until now. The results yield cosmic rulers to measure how the universe has expanded and to determine how much dark matter, dark energy, and even hard-to-detect neutrinos it contains.

Berkeley researchers have provided the most detailed look ever at the “regulatory particle” used by the proteasome – one of the most critical protein machines in living cells – to identify and degrade proteins marked for destruction. This new information holds implications for a broad range of vital biochemical processes, including transcription, DNA repair and the immune defense system.

Two teams at Fermilab and Berkeley Lab have independently made the largest direct measurements of the invisible scaffolding of the universe, using the gravitational lensing effect known as “cosmic shear” to build maps of the distribution of dark matter. Their methods show that surveys with ground-based telescopes can measure cosmic shear with enough accuracy to aid in better understanding the mysterious space-stretching effects of dark energy.