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Posts Tagged ‘biochemistry’

Puzzling Question in Bacterial Immune System Answered

January 29, 2014

Berkeley researchers have answered a central question about Cas9, an enzyme that plays an essential role in the bacterial immune system and is fast becoming a valuable tool for genetic engineering: How is Cas9 able to precisely discriminate between non-self DNA that must be degraded and self DNA that may be almost identical within genomes that are millions to billions of base pairs long.

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Shapes of Things to Come: Exotic Shapes for Liquid Drops Have Many Possible Uses

December 2, 2013

Through a combination of water, oil and nanoparticle surfactants plus an external field, spherical droplets are being transformed into ellipsoids and other unusual shapes that could find many valuable uses.

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Bringing Out the Best in X-ray Crystallography Data

November 4, 2013

Combining components of Rosetta and PHENIX, two successful software programs for creating 3D structural models of proteins and other biomolecules, Berkeley Lab researchers have created a new method for refining those models and making the best of available experimental data.

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Less Toxic Metabolites, More Chemical Product

October 29, 2013

By preventing the build-up of toxic metabolites in engineered microbes, a dynamic regulatory system developed at JBEI can help boost production of an advanced biofuel, a therapeutic drug, or other valuable chemical products. The system has already been used to double the production in E. coli of amorphadiene, a precursor to the premier antimalarial drug artemisinin.

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3D Dynamic Imaging of Soft Materials

October 2, 2013

Through a combination of transmission electron microscopy (TEM) and a unique graphene liquid cell, Berkeley Lab researchers have recorded the three-dimensional motion of DNA connected to gold nanocrystals, the first reported use of TEM for 3D dynamic imaging of soft materials.

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In Water as In Love, Likes Can Attract

September 18, 2013

Berkeley Lab researchers have shown that, contrary to the scientific axiom that only opposite charges attract, when hydrated in water, positively charged ions can pair up with one another.

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Microbial Who-Done-It For Biofuels

July 25, 2013

A multi-institutional collaboration led by researchers with the Joint BioEnergy Institute (JBEI) and Joint Genome Institute (JGI) has developed a promising technique for identifying microbial enzymes that can effectively deconstruct biomass into fuel sugars under refinery processing conditions.

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Clean, Green High Performance Biofuels from Carbon Dioxide

July 24, 2013

Researchers at the Joint BioEnergy Institute (JBEI) have engineered a microbe to produce high-performance diesel fuel from the greenhouse gas carbon dioxide rather than from the sugars in cellulosic biomass.

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Tiny Bubbles Hold Big Promise for NMR/MRI

July 15, 2013

Tiny bubbles carrying hyperpolarized xenon gas hold big promise for greatly increasing the sensitivity of NMR/MRI technologies.

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Of Aging Bones and Sunshine

July 10, 2013

Berkeley Lab researcher have shown that deficiencies in vitamin D – the sunshine vitamin – accelerates the aging of bone, reducing the quality and making it more susceptible to fracturing.

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