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Scientists Take Key Step Toward Custom-made Nanoscale Chemical Factories

Scientists have for the first time reengineered a building block of a geometric nanocompartment that occurs naturally in bacteria. The new design provides an entirely new functionality that greatly expands the potential for these compartments to serve as custom-made chemical factories.

New Weapon in the Fight Against Breast Cancer

Berkeley Lab researchers have developed the first clinically-relevant mouse model of human breast cancer to successfully express functional estrogen receptor positive adenocarcinomas.
This model should be a powerful tool for testing therapies for aggressive ER+ breast cancers and for studying luminal cancers — the most prevalent and deadliest forms of breast cancer.

Nanocarriers May Carry New Hope for Brain Cancer Therapy:

Berkeley Lab researchers have developed a new family of nanocarriers, called “3HM,” that meets all the size and stability requirements for effectively delivering therapeutic drugs to the brain for the treatment of a deadly form of cancer known as glioblastoma multiforme.

CinderBio Harnesses Extreme Microbes for Greener Industry

It’s no secret that extremophiles, or microbes that live in places like polar glaciers and toxic waste pools, may hold treasures worth billions. Now basic biology research has led to the formation of CinderBio, a startup co-founded by Berkeley Lab scientists Steve Yannone and Jill Fuss that produces heat- and acid-stable enzymes.

It Takes a Thief

The discovery by Berkeley Lab researchers of the structural basis by which bacteria are able to capture genetic information from viruses and other foreign invaders for use in their own immunological system holds promise for studying or correcting problems in human genomes.

Cellular Contamination Pathway for Plutonium, Other Heavy Elements, Identified

Scientists at Lawrence Berkeley National Laboratory have reported a major advance in understanding the biological chemistry of radioactive metals, opening up new avenues of research into strategies for remedial action in the event of possible human exposure to nuclear contaminants.

Major Innovation in Molecular Imaging Delivers Spatial and Spectral Info Simultaneously

Using physical chemistry methods to look at biology at the nanoscale, a Berkeley Lab researcher has invented a new technology to image single molecules with unprecedented spectral and spatial resolution, thus leading to the first “true-color” super-resolution microscope.

Atomic View of Microtubules

Berkeley Lab and UC Berkeley researchers produced an atomic view of microtubules that enabled them to identify the crucial role played by a family of end-binding proteins in regulating microtubule dynamic instability, the physical property that enables microtubules to play a crucial role in cell division.

Unlocking the Rice Immune System

JBEI, UC Davis and Berkeley Lab researchers have identified a bacterial signaling molecule that triggers an immunity response in rice plants, enabling the plants to resist a devastating blight disease. Rice is not only a staple food, it is the model for grass-type advanced biofuels.

Unravelling the Mysteries of Carbonic Acid

Berkeley Lab researchers report the first detailed characterization of the hydration structure of carbon dioxide gas as it dissolves in water to form carbonic acid. Though carbonic acid exists for only a fraction of a second, it imparts a lasting impact on Earth’s atmosphere and geology, and on the human body