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Boosting Biogasoline Production in Microbes

Researchers with the Joint BioEnergy Institute (JBEI) have identified microbial genes that can improve both the tolerance and the production of biogasoline in engineered strains of E. coli.

New Insights on Carbonic Acid in Water

A new study by Berkeley Lab researchers provides valuable new insight into aqueous carbonic acid with important implications for both geological and biological concerns.

Berkeley Lab and Scripps Research Institute Scientists Link ALS Progression to Increased Protein Instability

LA JOLLA, CA—October 13, 2014—A new study by scientists from The Scripps Research Institute (TSRI), Lawrence Berkeley National Laboratory (Berkeley Lab) and other institutions suggests a cause of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. “Our work supports a common theme whereby loss of protein stability leads to disease,” said John A.

RCas9: A Programmable RNA Editing Tool

A powerful scientific tool for editing the DNA instructions in a genome can now also be applied to RNA as Berkeley Lab researchers have demonstrated a means by which the CRISPR/Cas9 protein complex can be programmed to recognize and cleave RNA at sequence-specific target sites.

MaxBin: Automated Sorting Through Metagenomes

MaxBin is an automated software program for binning the genomes of individual microbial species from metagenomic sequences developed at the Joint BioEnergy Institute (JBEI).

Encyclopedia of How Genomes Function Gets Much Bigger

A big step in understanding the mysteries of the human genome was unveiled today in the form of three analyses that provide the most detailed comparison yet of how the genomes of the fruit fly, roundworm, and human function. The analyses will likely offer insights into how the information in the human genome regulates development, and how it is responsible for diseases.

Bionic Liquids from Lignin

Bionic liquids – solvents made from lignin and hemicellulose, two by-products of biofuel production – show great promise for liberating fermentable sugars from lignocellulose and improving the economics of biofuels refineries.

Of Metal Heads and Imaging

Berkeley Lab researchers are developing molecular imaging probes and techniques to study metals in the brain that have been linked to disorders such as Alzheimer’s and Parkinson’s diseases.

Life-Saving Dividends for Synthetic Biology Research: Microbial-Based Antimalarial Drug Shipped to Africa

A synthetic biology project begun 13 years ago by Jay Keasling was culminated with the announcement that a microbial-based version of the antimalarial drug artemisinin has been shipped to African nations where it is most needed.

“Imaging Life” Crosses Biological Boundaries, Introduces Integrated Bioimaging

Scientists studying the human tissues and entire living model organisms have an array of tools at their disposal to view the inner workings of our biological systems, from mass spectrometry imaging and optical microscopies, which can make pictures of entire tissues and organs, down to X-ray crystallography and NMR (nuclear magnetic resonance), which can image