Berkeley Lab scientists studied mice and found their risk of mammary cancer from low-dose radiation depends a great deal on their genetic makeup. They also learned key details about how genes and the cells immediately surrounding a tumor (also called the tumor microenvironment) affect cancer risk.
Berkeley Lab scientists have gained more insights into why older women are more susceptible to breast cancer. They found that as women age, the cells responsible for maintaining healthy breast tissue stop responding to their immediate surroundings, including mechanical cues that should prompt them to suppress nearby tumors.
A consortium led by Berkeley Lab scientists has conducted the largest survey yet of how information encoded in an animal genome is processed in different organs, stages of development, and environmental conditions. Their findings, based on fruit fly research, paint a new picture of how genes function in the nervous system and in response to environmental stress.
Berkeley Lab scientist Sylvain Costes has come up with a way to automate the job of screening for DNA damage, using a proprietary algorithm and a machine to scan specimens and objectively score the damaged DNA. Now he has launched Exogen Biotechnology to commercialize the technology and, he hopes, make tests for DNA damage as common as a cholesterol test.
Maybe you’ve seen the movies or played with toy Transformers, those shape-shifting machines that morph in response to whatever challenge they face. It turns out that DNA-repair machines in your cells use a similar approach to fight cancer and other diseases, according to new research led by Berkeley Lab scientists.
Berkeley Lab researchers have shown that aerobic glycolysis – glucose metabolism in the presence of oxygen – is not the consequence of the cancerous activity of malignant cells, as has been widely believed, but is itself a cancerous event.