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Posts Tagged ‘cancer’

Vast Gene-Expression Map Yields Neurological and Environmental Stress Insights

March 16, 2014

A consortium led by Berkeley Lab scientists has conducted the largest survey yet of how information encoded in an animal genome is processed in different organs, stages of development, and environmental conditions. Their findings, based on fruit fly research, paint a new picture of how genes function in the nervous system and in response to environmental stress.

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Berkeley Lab Startup Wants to Know How Damaged Your DNA Is

February 6, 2014

Berkeley Lab scientist Sylvain Costes has come up with a way to automate the job of screening for DNA damage, using a proprietary algorithm and a machine to scan specimens and objectively score the damaged DNA. Now he has launched Exogen Biotechnology to commercialize the technology and, he hopes, make tests for DNA damage as common as a cholesterol test.

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How a Shape-shifting DNA-repair Machine Fights Cancer

February 3, 2014

Maybe you’ve seen the movies or played with toy Transformers, those shape-shifting machines that morph in response to whatever challenge they face. It turns out that DNA-repair machines in your cells use a similar approach to fight cancer and other diseases, according to new research led by Berkeley Lab scientists.

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A Role of Sugar Uptake in Breast Cancer Revealed

December 18, 2013

Berkeley Lab researchers have shown that aerobic glycolysis – glucose metabolism in the presence of oxygen – is not the consequence of the cancerous activity of malignant cells, as has been widely believed, but is itself a cancerous event.

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Tiny Bubbles Hold Big Promise for NMR/MRI

July 15, 2013

Tiny bubbles carrying hyperpolarized xenon gas hold big promise for greatly increasing the sensitivity of NMR/MRI technologies.

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Cancerous Traffic Jams: Biomechanical Factor in Malignancies Identified

July 1, 2013

Berkeley Lab researchers have demonstrated that the malignant activity of a cellular protein system strongly linked to breast cancer can arise from what essentially are protein traffic jams.

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Berkeley Lab Confirms Thirdhand Smoke Causes DNA Damage

June 20, 2013

A study led by researchers from Lawrence Berkeley National Laboratory has found for the first time that thirdhand smoke—the noxious residue that clings to virtually all surfaces long after the secondhand smoke from a cigarette has cleared out—causes significant genetic damage in human cells.

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Berkeley Lab Researchers Discover How and Where Breast Tumor Cells Become Dormant and What Causes Them to Become Metastatic

June 3, 2013

Berkeley Lab researchers have identified the microenvironment surrounding microvasculature as a niche where dormant breast cancer cells may reside, and the sprouting of microvasculature blood vessels as the event that transforms dormant cancer cells into metastatic tumors.

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Berkeley Lab Discoveries Open New Hope for MMP Cancer Therapies

May 2, 2013

New evidence supports earlier findings that cancer therapy drugs based on a family of enzymes called metalloproteinases (MMPs) failed in clinical trials because they were aimed at the wrong target.

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Berkeley Lab Researchers Find New Clue to Clinical Trial Failures of MMP Cancer Therapies

February 11, 2013

Failure of Highly Touted MMP Cancer Therapies May Be Explained

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