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Posts Tagged ‘life sciences’

Vast Gene-Expression Map Yields Neurological and Environmental Stress Insights

March 16, 2014

A consortium led by Berkeley Lab scientists has conducted the largest survey yet of how information encoded in an animal genome is processed in different organs, stages of development, and environmental conditions. Their findings, based on fruit fly research, paint a new picture of how genes function in the nervous system and in response to environmental stress.

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First Look at How Individual Staphylococcus Cells Adhere to Nanostructures Could Lead to New Ways to Thwart Infections

March 4, 2014

A team of researchers led by Berkeley Lab scientists have explored how individual Staphylococcus cells glom onto metallic nanostructures of various shapes and sizes that are not much bigger than the cells themselves. Their work could lead to a more nuanced understanding of what makes a surface less inviting to bacteria.

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New Insight into an Emerging Genome-Editing Tool

February 6, 2014

A collaboration led by Berkeley Lab’s Jennifer Doudna and Eva Nogales has produced the first detailed look at the 3D structure of the Cas9 enzyme and how it partners with guide RNA to interact with target DNA. The results should enhance Cas9’s value and versatility as a genome-editing tool.

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Berkeley Lab Startup Wants to Know How Damaged Your DNA Is

February 6, 2014

Berkeley Lab scientist Sylvain Costes has come up with a way to automate the job of screening for DNA damage, using a proprietary algorithm and a machine to scan specimens and objectively score the damaged DNA. Now he has launched Exogen Biotechnology to commercialize the technology and, he hopes, make tests for DNA damage as common as a cholesterol test.

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How a Shape-shifting DNA-repair Machine Fights Cancer

February 3, 2014

Maybe you’ve seen the movies or played with toy Transformers, those shape-shifting machines that morph in response to whatever challenge they face. It turns out that DNA-repair machines in your cells use a similar approach to fight cancer and other diseases, according to new research led by Berkeley Lab scientists.

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Running may be better than walking for breast cancer survival

January 28, 2014

Previous studies have shown that breast cancer survivors who meet the current exercise recommendations are at 25% lower risk for dying from breast cancer. New research from Berkeley Lab suggests that exceeding the recommendations may provide greater protection, and that running may be better than walking.

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A Role of Sugar Uptake in Breast Cancer Revealed

December 18, 2013

Berkeley Lab researchers have shown that aerobic glycolysis – glucose metabolism in the presence of oxygen – is not the consequence of the cancerous activity of malignant cells, as has been widely believed, but is itself a cancerous event.

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Radiotherapy in Girls and the Risk of Breast Cancer Later in Life

September 11, 2013

Berkeley Lab researchers have helped determine why exposing young women and girls under the age of 20 to ionizing radiation can substantially raise the risk of their developing breast cancer later in life.

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New Biochip Holds Great Promise for Quickly Triaging People After Radiation Exposure

August 14, 2013

Berkeley Lab scientists have helped to develop a tiny chip that has big potential for quickly determining whether someone has been exposed to dangerous levels of ionizing radiation. The first-of-its-kind chip has an array of nanosensors that measure the concentrations of proteins that change after radiation exposure.

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Even Bacteria Use Social Networks

July 18, 2013

Using several imaging techniques, Berkeley Lab scientists found that a common soil bacterium stays connected by a network of chain-like membranes. They believe the bacterium uses its network to coordinate social activities—such as evading bacterial enemies and snaring prey—without revealing its location.

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