Time-lapse imaging can make complicated processes easier to grasp. Berkeley Lab scientists are using a similar approach to study how cells repair DNA damage. Microscopy images are acquired about every thirty minutes over a span of up to two days, and the resulting sequence of images shows ever-changing hotspots inside cells where DNA is under repair.
Berkeley Lab and UC Berkeley researchers produced an atomic view of microtubules that enabled them to identify the crucial role played by a family of end-binding proteins in regulating microtubule dynamic instability, the physical property that enables microtubules to play a crucial role in cell division.
Berkeley Lab scientists are developing a cell culture that could help researchers better identify chemicals that increase breast cancer susceptibility. The scientists will grow the culture using adult stem cells obtained from breast tissue. Their test will show if a chemical causes a breakdown in cell-to-cell communication, which is a fundamental defect of cancer.
The crew of the International Space Station will soon be joined by 180 mice from Berkeley Lab. Their mission: help scientists learn how space travel affects the immune system, organ development, and reproduction across generations. The mice are part of a Berkeley Lab experiment, funded by NASA this summer, which will shed light on how
With help from Berkeley Lab’s Advanced Light Source, scientists from UCLA recently designed a cage made of proteins. The nano-sized cage could lead to new biomaterials and new ways to deliver drugs inside cells. It boasts a record breaking 225-angstrom outside diameter, the largest to date for a designed protein assembly. It also has a 130-angstrom-diameter