Berkeley Lab scientists have learned new details about how an important tumor-suppressing protein, called p53, binds to the human genome. As with many things in life, they found that context makes a big difference.
With help from Berkeley Lab’s Advanced Light Source, scientists from UCLA recently designed a cage made of proteins. The nano-sized cage could lead to new biomaterials and new ways to deliver drugs inside cells. It boasts a record breaking 225-angstrom outside diameter, the largest to date for a designed protein assembly. It also has a 130-angstrom-diameter
A big step in understanding the mysteries of the human genome was unveiled today in the form of three analyses that provide the most detailed comparison yet of how the genomes of the fruit fly, roundworm, and human function. The analyses will likely offer insights into how the information in the human genome regulates development, and how it is responsible for diseases.
Excessive Running or Walking May Eliminate Health Gains in Heart Attack Survivors, Finds Berkeley Lab Research
It’s an all-too familiar scenario for many people. You sprain your ankle or twist your knee. If you’re an adult, the initial pain is followed by a long road of recovery, with no promise that the torn ligament or tendon will ever regain its full strength. That’s because tendon and ligament cells in adults produce
Berkeley Lab has won three 2014 R&D 100 awards. This year’s winners include a fast way to analyze the chemical composition of cells, a suite of genetic tools to improve crops, and a method to screen images of 3-D cell cultures for cancer cells. The technologies could lead to advances in biofuels, food crops, drug development, and biomaterials, and a to better understanding of microbial communities, to name a few potential benefits.
Berkeley Lab scientists have gained more insights into why older women are more susceptible to breast cancer. They found that as women age, the cells responsible for maintaining healthy breast tissue stop responding to their immediate surroundings, including mechanical cues that should prompt them to suppress nearby tumors.
A consortium led by Berkeley Lab scientists has conducted the largest survey yet of how information encoded in an animal genome is processed in different organs, stages of development, and environmental conditions. Their findings, based on fruit fly research, paint a new picture of how genes function in the nervous system and in response to environmental stress.
First Look at How Individual Staphylococcus Cells Adhere to Nanostructures Could Lead to New Ways to Thwart Infections
A team of researchers led by Berkeley Lab scientists have explored how individual Staphylococcus cells glom onto metallic nanostructures of various shapes and sizes that are not much bigger than the cells themselves. Their work could lead to a more nuanced understanding of what makes a surface less inviting to bacteria.