Nearly ten years ago, a group of Israeli clinical researchers emailed Berkeley Lab geneticist Len Pennacchio to ask for his team’s help in solving the mystery of a rare inherited disease that caused extreme, and sometimes fatal, chronic diarrhea in children. Now, following an arduous investigative odyssey that expanded our understanding of regulatory sequences in the human genome, the multinational scientific group has announced the discovery of the genetic explanation for this disease.
Experiments at Berkeley Lab’s Advanced Light Source detailed the structure of a grouping of amino acids that are part of an important signaling protein.
Adapted from an original release published by Lawrence Livermore National Laboratory. Read the full story here Plant cell walls contain a renewable, nearly-limitless supply of sugar that can be used as a carbon source for microbe-based chemical and biofuel production. However, retrieving these sugars isn’t all that easy. Imidazolium ionic liquid (IIL) solvents are some
A new biosynthetic production pathway developed by scientists at the Joint BioEnergy Institute could provide a sustainable alternative to conventional synthetic blue dye. The highly efficient fungi-based platform may also open the door for producing many other valuable biological compounds that are currently very hard to manufacture.
Marking a step forward in Berkeley Lab’s vision to expand the footprint of the biological and environmental sciences, the Integrative Genomics Building (IGB) was dedicated during a two-hour ceremony that culminated in the cutting of a double helix ribbon representing DNA. By uniting leading experts and world-class technologies under one roof, the IGB will help transform plant and microbial genomics research into solutions for today’s most pressing environmental and energy issues.
Researchers at Lawrence Berkeley National Laboratory have developed a new chemical separation method that is vastly more efficient than conventional processes, opening the door to faster discovery of new elements, easier nuclear fuel reprocessing, and, most tantalizing, a better way to attain actinium-225, a promising therapeutic isotope for cancer treatment.
An open-source RNA analysis platform has been successfully used on plant cells for the first time – a breakthrough that could herald a new era of fundamental research and bolster efforts to engineer more efficient food and biofuel crop plants. The technology, called Drop-seq, is a method for measuring the RNA present in individual cells, allowing scientists to see what genes are being expressed and how this relates to the specific functions of different cell types.
Researchers in Berkeley Lab’s Computational Research Division are applying deep learning and analytics to electronic health record (EHR) data to help the Veterans Administration address a host of medical and psychological challenges affecting many of the nation’s 700,000 military veterans.
Mice have been instrumental in the study of cancer, but like all animal models of human diseases, they have their limitations. For stomach cancer in particular, mice have historically been regarded as quite poor research organisms because rodents rarely develop spontaneous stomach tumors. But results from a new study are about to shake up the paradigm.
Mina Bissell, a distinguished scientist at the Berkeley Lab, has been selected to receive two prestigious awards for her pioneering contributions to breast cancer biology and medicine.