A test developed by Berkeley Lab scientists can quickly and easily detect whether sperm cells are carrying chromosomal defects, an advance that will help men who have undergone cancer treatment father healthy children.
Researchers from Berkeley Lab and Los Alamos National Laboratory have developed new methods for the large-scale production, purification, and use of the radioisotope cerium-134, which could serve as a PET imaging radioisotope for a highly targeted cancer treatment known as alpha-particle therapy.
Sometimes, when something is broken, the first step to fixing it is to break it even more. Scientists have discovered this is the case for a human DNA repair protein that functions by marking and then further breaking damaged DNA. Their surprising findings have provided much-needed insight into how DNA repair works in healthy cells, as well as how different mutations can translate into different diseases and cancer.
Distinguished senior scientist Mina Bissell is one of five recipients of the 2020 Canada Gairdner International Award – an annual honor given to scientists who have contributed to transformative human health research.
An investigational cancer drug that targets tumors caused by mutations in the KRAS gene will be evaluated in phase 2 clinical trials, following promising safety and efficacy results in preliminary human studies and excellent results in animal studies. The drug, developed by Amgen and currently referred to as AMG 510, is the first therapy to reach clinical
Mice have been instrumental in the study of cancer, but like all animal models of human diseases, they have their limitations. For stomach cancer in particular, mice have historically been regarded as quite poor research organisms because rodents rarely develop spontaneous stomach tumors. But results from a new study are about to shake up the paradigm.
Mina Bissell, a distinguished scientist at the Berkeley Lab, has been selected to receive two prestigious awards for her pioneering contributions to breast cancer biology and medicine.
A research team has demonstrated how light-emitting nanoparticles, developed at Berkeley Lab, can be used to see deep in living tissue. Researchers hope they can be made to attach to specific components of cells to serve in an advanced imaging system that can pinpoint even single cancer cells.
Researchers at Berkeley Lab identified thirdhand smoke, the toxic residues that linger on indoor surfaces and in dust long after a cigarette has been extinguished, as a health hazard nearly 10 years ago. Now a new study has found that it also increases lung cancer risk in mice.
A protein called XPG plays a previously unknown and critical role helping to maintain genome stability in human cells. It may also help prevent breast, ovarian, and other cancers associated with defective BRCA genes.