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Exploring Human Origins in the Uncharted Territory of Our Chromosomes

A group of geneticists from Berkeley Lab, UC Davis, UC Santa Cruz, and UC Berkeley are unraveling new details about human evolution by studying the uniquely regulated portion of our chromosomes that surround the centromeres. These stretches of DNA – termed centromere-proximal regions (CPRs) – are largely composed of highly repetitive, mostly non-gene-coding sequences that are