A test developed by Berkeley Lab scientists can quickly and easily detect whether sperm cells are carrying chromosomal defects, an advance that will help men who have undergone cancer treatment father healthy children.
A team of biologists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells. The structural map – which is now published in the journal PNAS, but has been open-access for the scientific community since August – has laid the groundwork for new antiviral treatments and enabled further investigations into how the newly emerged virus ravages the human body.
A new approach for studying phages-bacteria interactions will help scientists study the intricate offensive and defensive chemical tactics used by parasite and host. These microscopic battles have implications for medicine development, agricultural research, and climate science.
Berkeley Lab statistician Paul Williams seeks to explain how genetics and external factors interact to shape alcohol consumption, lung function, and weight gain – aspects of health that are on many of our minds during the the coronavirus pandemic and wildfires.
Berkeley Lab bioscientists are part of a nationwide research project, called ENCODE, that has generated a detailed atlas of the molecular elements that regulate our genes. This enormous resource will help all human biology research moving forward.
Our biomanufacturing experts are helping accelerate the development of new COVID-19-fighting technologies. Learn how the scientists at the ABPDU are collaborating with biotech companies to scale up and optimize production of coronavirus-targeting antibodies and a highly accurate rapid testing system.
Even an underground experiment 4,600 feet below a mountain in Central Italy, and a telescope instrument more than a mile high atop an Arizona mountaintop could not escape the impacts of the COVID-19 pandemic. In these videos, a Berkeley Lab scientist and two Berkeley Lab-affiliated researchers share their experiences of working in international collaborations during the COVID-19 pandemic.
Sometimes, when something is broken, the first step to fixing it is to break it even more. Scientists have discovered this is the case for a human DNA repair protein that functions by marking and then further breaking damaged DNA. Their surprising findings have provided much-needed insight into how DNA repair works in healthy cells, as well as how different mutations can translate into different diseases and cancer.
One of the many unanswered scientific questions about COVID-19 is whether it is seasonal like the flu – waning in warm summer months then resurging in the fall and winter. Now scientists at Lawrence Berkeley National Laboratory are launching a project to apply machine-learning methods to a plethora of health and environmental datasets, combined with high-resolution climate models and seasonal forecasts, to tease out the answer.
An international scientific team has discovered a neutralizing antibody, derived from the blood of a SARS survivor, that inhibits the closely related COVID-19-causing coronavirus. In a paper published this week in Nature, the scientists note that the antibody is already on an accelerated development path toward clinical trials.