News Center

Designing Cyclic Oligomers: Greater Than the Sum of Their Parts

-Written By Lida Gifford Cyclic proteins that assemble from multiple identical subunits (homo-oligomers) play key roles in many biological processes, including cell signaling and enzymatic catalysis and protein function. Researchers in Berkeley Lab’s Molecular Biophysics and Integrated Bioimaging (MBIB) Division worked with University of Washington’s David Baker, who led a team to design in silico

Researchers Gain Insight into Protein Critical to Zika Virus Reproduction

Berkeley Lab researchers collaborated with colleagues from the University of Indiana and Texas A&M University to solve the atomic structure of a Zika virus protein that is key to viral reproduction. The X-ray studies were conducted at the Advanced Light Source in the Berkeley Center for Structural Biology.

Cryo-Electron Microscopy Achieves Unprecedented Resolution Using New Computational Methods

Cryo-electron microscopy (cryo-EM)—which enables the visualization of viruses, proteins, and other biological structures at the molecular level—is a critical tool used to advance biochemical knowledge. Now Lawrence Berkeley National Laboratory (Berkeley Lab) researchers have extended cryo-EM’s impact further by developing a new computational algorithm that was instrumental in constructing a 3-D atomic-scale model of bacteriophage

Getting to Know Meteors Better

X-ray studies of meteorite samples, conducted by NASA and Berkeley Lab researchers, could help gauge threats to Earth by providing new insights on the microscopic makeup of asteroids and how they break up in the atmosphere.

A New Paradigm in Parachute Design

X-ray-based experiments at Berkeley Lab will simulate—in microscopic detail—spacecraft parachute fabric performance in the extreme conditions of other planets’ atmospheres.

The Heat is On

NASA is developing a new family of flexible heat-shield systems with a woven carbon-fiber base material, and is using X-rays at Berkeley Lab’s Advanced Light Source to test the designs.

When Rocket Science Meets X-ray Science

NASA and Berkeley Lab researchers have teamed up to explore next-generation spacecraft materials at the microscale using an X-ray technique that produces 3-D images. This work could help ensure future spacecraft survive the rigors of otherworldly atmospheres.

Workshop Focuses on the Unique Science Enabled by ALS-U

Visiting scientists gave input during a workshop last week on the range of new X-ray science made possible by a planned upgrade of the Advanced Light Source.

Chemistry on the Edge: Study Pinpoints Most Active Areas of Reactions on Nanoscale Particles

Defects and jagged surfaces at the edges of nanosized platinum and gold particles are key hot spots for chemical reactivity, researchers confirmed using a unique infrared probe.

7 Imaging Tools Pushing Science Forward

Berkeley Lab scientists are developing new ways to see the unseen. Here are seven imaging advances (recently reported in our News Center) that are helping to push science forward, from developing better batteries to peering inside cells to exploring the nature of the universe.   1. Seeing DNA nanostructures in 3-D DNA segments can serve as a