Berkeley Lab researchers have achieved unprecedented success in modifying a microbe to efficiently produce a compound of interest using a computational model and CRISPR-based gene editing. Their approach could dramatically speed up the research and development phase for new biomanufacturing processes, getting advanced bio-based products, such as sustainable fuels and plastic alternatives, on the shelves faster.
Three scientists at Berkeley Lab have been selected by the U.S. Department of Energy’s Office of Science to receive significant funding for research through its Early Career Research Program (ECRP). In addition, three faculty scientists with joint appointments at Berkeley Lab and UC Berkeley will receive ECRP funding through their UC Berkeley affiliations.
A study of how fungi sense and respond to available food helps explain nutrient recycling and opens the door to better methods for producing bio-based products.
Berkeley Lab’s Rebecca Abergel, Roland Bürgmann, Cheryl A. Kerfeld, Michael Manga, Natalie Roe, and David V. Schaffer have been named Fellows of the American Association for the Advancement of Science (AAAS). Election as a AAAS Fellow is an honor bestowed upon AAAS members by their peers.
An international team of scientists led by the Joint Genome Institute has developed a genetic engineering tool that makes producing and analyzing microbial secondary metabolites – the basis for many important agricultural, industrial, and medical products – much easier than before, and could even lead to breakthroughs in biomanufacturing.
The National Microbiome Data Collaborative (NMDC), a new initiative aimed at empowering microbiome research, is gearing up its pilot phase after receiving $10 million of funding from the U.S. Department of Energy Office of Science.
Long ago, during the European Renaissance, Leonardo da Vinci wrote that we humans “know more about the movement of celestial bodies than about the soil underfoot.” Five hundred years and innumerable technological and scientific advances later, his sentiment still holds true. But that could soon change. A new study in Nature Communications details how an improved method for studying microbes in the soil will help scientists understand both fine-grained details and large-scale cycles of the environment.
Marking a step forward in Berkeley Lab’s vision to expand the footprint of the biological and environmental sciences, the Integrative Genomics Building (IGB) was dedicated during a two-hour ceremony that culminated in the cutting of a double helix ribbon representing DNA. By uniting leading experts and world-class technologies under one roof, the IGB will help transform plant and microbial genomics research into solutions for today’s most pressing environmental and energy issues.
An open-source RNA analysis platform has been successfully used on plant cells for the first time – a breakthrough that could herald a new era of fundamental research and bolster efforts to engineer more efficient food and biofuel crop plants. The technology, called Drop-seq, is a method for measuring the RNA present in individual cells, allowing scientists to see what genes are being expressed and how this relates to the specific functions of different cell types.
Specific compounds are transformed by and strongly associated with specific bacteria in native biological soil crust (biocrust) using a suite of tools called “exometabolomics.” Understanding how microbial communities in biocrusts adapt to harsh environments could shed light on the roles of soil microbes in the global carbon cycle.