As the name implies, crystallography requires crystals – specifically, purified samples of the molecule of interest, coaxed into a crystal form. But most molecules form powders composed of jumbled granules, not picture-ready crystals. A new computer algorithm, combined with a state-of-the-art laser, can adapt X-ray crystallography for the many not-so-neat-and-tidy compounds that scientists seek to study.
Researchers develop an efficient method for studying fast biochemical reactions as they happen in real time
A new process combining infrared light analysis and machine learning shows potential to break barriers in disease detection.
This video shows steps of the enzymatic reaction that makes a double-ringed molecule, which is the structural starting point to produce molecules in a large class of antibiotics. (Credit: Patrick Rabe/Oxford University) Scientists who specialize in studying the atom-by-atom choreography of enzymes have revealed new insights into the function of isopenicillin N synthase, an
-By Emily Scott Ten years ago, Lawrence Berkeley National Laboratory announced the opening of a brand new, 15,000-square-foot facility full of stainless steel state-of-the-art bioprocessing equipment – what we now know as the Advanced Biofuels and Bioproducts Process Development Unit, or ABPDU, was officially open for business. Funded by the U.S. Department of Energy’s Bioenergy
Scientists from three national labs have published a comprehensive study that – alongside other recent, complementary studies of coronavirus proteins and genetics – represents the first step toward developing treatments for COVID-19.
A Berkeley Lab-led team is digging into the bizarre bacteria-produced nanomachines that could fast-track medicine and microbiome science
Scientists at Berkeley Lab have demonstrated how to image samples of heavy elements as small as a single nanogram. The new approach will help scientists advance new technologies for medical imaging and cancer therapies.
Berkeley Lab scientist who leads the development of a widely used data analysis software discusses the role of structural biology in vaccine and antiviral research.
As the COVID-19 pandemic enters its second year, scientists are still working to understand how the new strain of coronavirus evolved, and how it became so much more dangerous than other coronaviruses, which humans have been living alongside for millennia. Virologists and epidemiologists worldwide have speculated for months that a protein called ORF8 likely holds the answer, and a recent study by Berkeley Lab scientists has helped confirm this hypothesis.