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Safely Studying Dangerous Infections Just Got a Lot Easier

Soft X-ray tomography – a way to take gorgeously high-resolution, 3D images of cells – can help us study infections without risk of contamination. And now, the whole process takes just a fraction of the time and preparation required by other imaging methods.

Crystallography for the Misfit Crystals

As the name implies, crystallography requires crystals – specifically, purified samples of the molecule of interest, coaxed into a crystal form. But most molecules form powders composed of jumbled granules, not picture-ready crystals. A new computer algorithm, combined with a state-of-the-art laser, can adapt X-ray crystallography for the many not-so-neat-and-tidy compounds that scientists seek to study.

New Technique Gets the Drop On Enzyme Reactions

Researchers develop an efficient method for studying fast biochemical reactions as they happen in real time

Cell ‘Fingerprinting’ Could Yield Long-Awaited Alzheimer’s Disease Diagnostic

A new process combining infrared light analysis and machine learning shows potential to break barriers in disease detection.

Enzyme Action Movie Shows How Nature Makes Penicillins

This video shows steps of the enzymatic reaction that makes a double-ringed molecule, which is the structural starting point to produce molecules in a large class of antibiotics. (Credit: Patrick Rabe/Oxford University)   Scientists who specialize in studying the atom-by-atom choreography of enzymes have revealed new insights into the function of isopenicillin N synthase, an

ABPDU Celebrates a Decade of Bio-Innovation

-By Emily Scott Ten years ago, Lawrence Berkeley National Laboratory announced the opening of a brand new, 15,000-square-foot facility full of stainless steel state-of-the-art bioprocessing equipment – what we now know as the Advanced Biofuels and Bioproducts Process Development Unit, or ABPDU, was officially open for business. Funded by the U.S. Department of Energy’s Bioenergy

Deconstructing the Infectious Machinery of the SARS-CoV-2 Virus

Scientists from three national labs have published a comprehensive study that – alongside other recent, complementary studies of coronavirus proteins and genetics – represents the first step toward developing treatments for COVID-19.

The Incredible Bacterial ‘Homing Missiles’ That Scientists Want to Harness

A Berkeley Lab-led team is digging into the bizarre bacteria-produced nanomachines that could fast-track medicine and microbiome science

Do You Know the Way to Berkelium, Californium?

Scientists at Berkeley Lab have demonstrated how to image samples of heavy elements as small as a single nanogram. The new approach will help scientists advance new technologies for medical imaging and cancer therapies.

Scientist Q&A: The Molecular Imaging Behind COVID-19 Breakthroughs

Berkeley Lab scientist who leads the development of a widely used data analysis software discusses the role of structural biology in vaccine and antiviral research.