Subtle memory deficits are common in normal aging as well as Alzheimer disease (AD), the leading cause of dementia in older adults. This makes AD difficult to diagnose in its early stages. As there is currently no effective treatment to slow or stop the progression of AD, it is important to identify early pathological brain
A new material called “avalanching nanoparticles” co-designed by Berkeley Lab could lead to simple, high-resolution bioimaging in real time.
A trio of Berkeley Lab scientists has been awarded a grant by the Gordon and Betty Moore Foundation to develop a unique microscopy technology that can be used to study symbiosis in aquatic microbes – biological relationships that have a large influence on ecosystems and the planet’s climate. The grant is part of a three-year, $19-million project within the Foundation’s Symbiosis in Aquatic Systems Initiative.
Vaccines, which help the body recognize infectious microorganisms and stage a stronger and faster response, are made up of proteins that are specific to each type of microorganism. In the case of a virus, viral proteins – or antigens – can sometimes be attached to a protein scaffold to help mimic the shape of the
Using a unique combination of nanoscale imaging and chemical analysis, an international team of researchers has revealed a key step in the molecular mechanism behind the water splitting reaction of photosynthesis, a finding that could help inform the design of renewable energy technology.
Experiments at Berkeley Lab’s Advanced Light Source detailed the structure of a grouping of amino acids that are part of an important signaling protein.
Researchers at Berkeley Lab have used one of the most advanced microscopes in the world to reveal the structure of a large protein complex crucial to photosynthesis, the process by which plants convert sunlight into cellular energy. The finding, published in the journal Nature, will allow scientists to explore, for the first time, how the complex functions and could have implications for the production of a variety of bioproducts, including plastic alternatives and biofuels.
Researchers at Lawrence Berkeley National Laboratory and UC Berkeley have combined cutting-edge cryo-electron microscopy (cryo-EM) with computational molecular modeling to produce a near atomic-resolution model of the interaction between microtubules – crucial components of eukaryotic cell ultrastructure – and microtubule-associated proteins called tau.