Berkeley Lab researchers have achieved unprecedented success in modifying a microbe to efficiently produce a compound of interest using a computational model and CRISPR-based gene editing. Their approach could dramatically speed up the research and development phase for new biomanufacturing processes, getting advanced bio-based products, such as sustainable fuels and plastic alternatives, on the shelves faster.
If you’ve eaten vegan burgers that taste like meat or used synthetic collagen in your beauty routine – both products that are “grown” in the lab – then you’ve benefited from synthetic biology. It’s a field rife with potential, as it allows scientists to design biological systems to specification, such as engineering a microbe to produce a cancer-fighting agent. Yet conventional methods of bioengineering are slow and laborious, with trial and error being the main approach.
Researchers at JBEI have developed a new set of synthetic biology tools that could unlock advanced plant engineering.
A new biosynthetic production pathway developed by scientists at the Joint BioEnergy Institute could provide a sustainable alternative to conventional synthetic blue dye. The highly efficient fungi-based platform may also open the door for producing many other valuable biological compounds that are currently very hard to manufacture.
In what could address a critical bottleneck in biology research, Berkeley Lab researchers announced they have pioneered a new way to synthesize DNA sequences through a creative use of enzymes that promises to be faster, cheaper, and more accurate.