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X-ray imaging Reveals Insights into a Natural Mosquito-Killing Compound

Many of the chemicals used to deter or eliminate disease-carrying mosquitoes can pollute ecosystems and drive the evolution of even more problematic, insecticide-resistant species – but thankfully, we may have better options soon.

One Step Closer to a Fast-Charging Battery

Berkeley Lab researchers, working with a team at Brookhaven National Laboratory, have made a key discovery about the dynamic structural changes in a material called lithium titanate, putting scientists one step closer to achieving a fast-charging lithium battery. The scientists used both experimental and computational techniques to examine lithium titanate, or LTO, while it was

New Library of Artificial Antibodies Could Target Pathogens With Molecular Precision

A research team led by Berkeley Lab has developed a technique that could accelerate the design of artificial antibodies for biomedical applications – from sensing technologies that detect and neutralize infectious viruses and bacteria to the early detection of Alzheimer’s.

Berkeley Lab Helps Reveal How Dinosaur Blood Vessels Can Preserve Through the Ages

A team of scientists used infrared and X-ray imaging performed at Berkeley Lab’s Advanced Light Source to determine the chemical mechanisms that allow soft tissue structures to persist in dinosaur bones – countering the long-standing scientific dogma that protein-based body parts can’t survive more than 1 million years.

Joint Genome Institute Study Reveals Diversity of Giant Viruses Worldwide

A team led by the Joint Genome Institute has reconstructed the genomes of 2,074 large and giant viruses found across the globe, drastically increasing the number of known viruses and providing a resource for future studies on this poorly understood group of viruses, called nucleocytoplasmic large DNA viruses.

X-Ray Technology Sheds New Light on Antibiotic Synthesis

Atomic-scale structural analyses performed at Berkeley Lab’s Advanced Light Source are helping scientists understand the inner workings of the enzyme “assembly lines” that microbes use to produce an important class of compounds, many of which have uses as antibiotics, antifungals, and immunosuppressants.

Unique Cancer Drug Discovered With Help From Advanced Light Source Begins Historic Clinical Trial

An investigational cancer drug that targets tumors caused by mutations in the KRAS gene will be evaluated in phase 2 clinical trials, following promising safety and efficacy results in preliminary human studies and excellent results in animal studies. The drug, developed by Amgen and currently referred to as AMG 510, is the first therapy to reach clinical

These Artificial Proteins Have a Firm Grasp on Heavy Metals

A team of scientists led by Berkeley Lab has developed a library of artificial proteins or “peptoids” that effectively “chelate” or bind to lanthanides and actinides, heavy metals that make up the so-called f-block elements at the bottom of the periodic table. The new library offers researchers an automated, high-throughput method for precisely designing new

In Tooth Enamel, Slight Crystal Misorientations Stop Cracks in Their Tracks

Adult teeth can last a lifetime, withstanding enormous chewing pressures applied hundreds of times each day for decades. In a recent study published in Nature Communications, researchers discovered a natural toughening mechanism: small misorientations among the nanocrystal building blocks of human tooth enamel. Enamel is composed of hydroxyapatite, a biomineral that forms long and thin

A Matchmaker for Microbiomes

A unique neural network tool is making it possible to accurately infer the interactions between the microbes that are present in a community and the metabolites they produce – a capability that will greatly advance research into the microbiomes in the environment and inside our bodies.