A test developed by Berkeley Lab scientists can quickly and easily detect whether sperm cells are carrying chromosomal defects, an advance that will help men who have undergone cancer treatment father healthy children.
A team of biologists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells. The structural map – which is now published in the journal PNAS, but has been open-access for the scientific community since August – has laid the groundwork for new antiviral treatments and enabled further investigations into how the newly emerged virus ravages the human body.
Researchers from Berkeley Lab and Los Alamos National Laboratory have developed new methods for the large-scale production, purification, and use of the radioisotope cerium-134, which could serve as a PET imaging radioisotope for a highly targeted cancer treatment known as alpha-particle therapy.
A new approach for studying phages-bacteria interactions will help scientists study the intricate offensive and defensive chemical tactics used by parasite and host. These microscopic battles have implications for medicine development, agricultural research, and climate science.
Scientists have determined the structure of a unique enzyme, produced by a species of methane-eating bacteria, that converts the greenhouse gas into methanol – a highly versatile liquid fuel and industrial product ingredient.
Scientists from the DOE Joint Genome Institute and DOE Systems Biology Knowledgebase have launched a public database of 52,515 microbial draft genomes generated from environmental samples collected around the world. The new resource, known as the Genomes from Earth’s Microbiomes (GEM) catalog, provides extensive insight into the many types of microbes that are impossible to grow in a lab, and expands the known diversity of bacteria and archaea by 44%.
Berkeley Lab researchers have achieved unprecedented success in modifying a microbe to efficiently produce a compound of interest using a computational model and CRISPR-based gene editing. Their approach could dramatically speed up the research and development phase for new biomanufacturing processes, getting advanced bio-based products, such as sustainable fuels and plastic alternatives, on the shelves faster.
To see, in microscopic detail, what makes the diabolical ironclad beetle so uniquely sturdy, researchers used an X-ray imaging technique at Berkeley Lab’s Advanced Light Source synchrotron, and other techniques, to explore a protective covering known as the “elytra,” its abdomen, and other parts.
Berkeley Lab statistician Paul Williams seeks to explain how genetics and external factors interact to shape alcohol consumption, lung function, and weight gain – aspects of health that are on many of our minds during the the coronavirus pandemic and wildfires.
Microbiomes are integral to all life, from human health and food security to ecosystem processes and global nutrient cycling. Collaborative research – performed by scientists spanning the vast biological and bioinformatics fields – is key to developing a predictive understanding of microbiome function and could lead to advancements in areas such as biomanufacturing, food production,