Scientists have determined the structure of a unique enzyme, produced by a species of methane-eating bacteria, that converts the greenhouse gas into methanol – a highly versatile liquid fuel and industrial product ingredient.
Scientists from the DOE Joint Genome Institute and DOE Systems Biology Knowledgebase have launched a public database of 52,515 microbial draft genomes generated from environmental samples collected around the world. The new resource, known as the Genomes from Earth’s Microbiomes (GEM) catalog, provides extensive insight into the many types of microbes that are impossible to grow in a lab, and expands the known diversity of bacteria and archaea by 44%.
Berkeley Lab researchers have achieved unprecedented success in modifying a microbe to efficiently produce a compound of interest using a computational model and CRISPR-based gene editing. Their approach could dramatically speed up the research and development phase for new biomanufacturing processes, getting advanced bio-based products, such as sustainable fuels and plastic alternatives, on the shelves faster.
To see, in microscopic detail, what makes the diabolical ironclad beetle so uniquely sturdy, researchers used an X-ray imaging technique at Berkeley Lab’s Advanced Light Source synchrotron, and other techniques, to explore a protective covering known as the “elytra,” its abdomen, and other parts.
Berkeley Lab statistician Paul Williams seeks to explain how genetics and external factors interact to shape alcohol consumption, lung function, and weight gain – aspects of health that are on many of our minds during the the coronavirus pandemic and wildfires.
Microbiomes are integral to all life, from human health and food security to ecosystem processes and global nutrient cycling. Collaborative research – performed by scientists spanning the vast biological and bioinformatics fields – is key to developing a predictive understanding of microbiome function and could lead to advancements in areas such as biomanufacturing, food production,
Berkeley Lab bioscientists are part of a nationwide research project, called ENCODE, that has generated a detailed atlas of the molecular elements that regulate our genes. This enormous resource will help all human biology research moving forward.
Our biomanufacturing experts are helping accelerate the development of new COVID-19-fighting technologies. Learn how the scientists at the ABPDU are collaborating with biotech companies to scale up and optimize production of coronavirus-targeting antibodies and a highly accurate rapid testing system.
Even an underground experiment 4,600 feet below a mountain in Central Italy, and a telescope instrument more than a mile high atop an Arizona mountaintop could not escape the impacts of the COVID-19 pandemic. In these videos, a Berkeley Lab scientist and two Berkeley Lab-affiliated researchers share their experiences of working in international collaborations during the COVID-19 pandemic.
Sometimes, when something is broken, the first step to fixing it is to break it even more. Scientists have discovered this is the case for a human DNA repair protein that functions by marking and then further breaking damaged DNA. Their surprising findings have provided much-needed insight into how DNA repair works in healthy cells, as well as how different mutations can translate into different diseases and cancer.