Biomanufacturing – harnessing biological processes in cells and microbes to design and manufacture products – is revolutionizing how we make everything from futuristic consumer goods to sustainable fuels to breakthrough medicines. Every biomanufactured product can be traced back to discoveries in the lab, but translating that science into a real-world product can be tricky. Berkeley Lab is helping to move great ideas, like outdoor gear made from algae oil, from conception to commercialization.
An investigational cancer drug that targets tumors caused by mutations in the KRAS gene will be evaluated in phase 2 clinical trials, following promising safety and efficacy results in preliminary human studies and excellent results in animal studies. The drug, developed by Amgen and currently referred to as AMG 510, is the first therapy to reach clinical
Berkeley Lab’s Chris Mungall and Nomi Harris explain how agreeing on precise definitions of each rare disease can lead to more accurate diagnoses and better treatments, and share new evidence showing this endeavor is more important than ever.
A unique neural network tool is making it possible to accurately infer the interactions between the microbes that are present in a community and the metabolites they produce – a capability that will greatly advance research into the microbiomes in the environment and inside our bodies.
A new test agent can easily and efficiently detect the misfolded protein aggregates that cause devastating neurological diseases in blood samples. The technology could lead to early diagnosis of prion, Alzheimer’s, and Parkinson’s diseases for the first time.
The gut microbiome undergoes rapid and dramatic changes in species composition and gene expression when the host switches between eating cooked or raw vegetables, according to a new study published in Nature Microbiology.
An international team of scientists led by the Joint Genome Institute has developed a genetic engineering tool that makes producing and analyzing microbial secondary metabolites – the basis for many important agricultural, industrial, and medical products – much easier than before, and could even lead to breakthroughs in biomanufacturing.
As the need for energy security grows, scientists are investigating nonfood biomass sources that can be used to create valuable biofuels and bioproducts. Among these sources is municipal solid waste (MSW) — in other words, trash that’s produced every day around the world in significant amounts.
Marketed as a healthier alternative to cigarettes, a new class of tobacco products called heat-not-burn devices is quickly gaining in popularity across the globe. A study by Berkeley Lab’s Indoor Environment Group shows that, although the chemical emissions from these devices are lower than those produced by conventional cigarettes, they are still high enough to raise concern.
A new study by researchers at Lawrence Berkeley National Laboratory shows that if every building in California sported “cool” roofs by 2050, these roofs would help contribute to protecting urbanites from the consequences of dangerous heatwaves.