Berkeley Lab researchers have achieved unprecedented success in modifying a microbe to efficiently produce a compound of interest using a computational model and CRISPR-based gene editing. Their approach could dramatically speed up the research and development phase for new biomanufacturing processes, getting advanced bio-based products, such as sustainable fuels and plastic alternatives, on the shelves faster.
Plants can produce a wide range of molecules, many of which help them fight off harmful pests and pathogens. Biologists have harnessed this ability to produce many molecules important for human health — aspirin and the antimalarial drug artemisinin, for example, are derived from plants. Now, scientists at the Joint BioEnergy Institute (JBEI) are using
Researchers at Berkeley Lab have transformed lignin, a waste product of the paper industry, into a precursor for a useful chemical with a wide range of potential applications. Lignin is a complex material found in plant cell walls that is notoriously difficult to break down and turn into something useful. Typically, lignin is burned for
If you’ve eaten vegan burgers that taste like meat or used synthetic collagen in your beauty routine – both products that are “grown” in the lab – then you’ve benefited from synthetic biology. It’s a field rife with potential, as it allows scientists to design biological systems to specification, such as engineering a microbe to produce a cancer-fighting agent. Yet conventional methods of bioengineering are slow and laborious, with trial and error being the main approach.
One strategy to make biofuels more competitive is to make plants do some of the work themselves. Scientists can engineer plants to produce valuable chemical compounds, or bioproducts, as they grow. Then the bioproducts can be extracted from the plant and the remaining plant material can be converted into fuel. But one important part of this strategy has remained unclear — exactly how much of a particular bioproduct would plants need to make in order to make the process economically feasible?
As the need for energy security grows, scientists are investigating nonfood biomass sources that can be used to create valuable biofuels and bioproducts. Among these sources is municipal solid waste (MSW) — in other words, trash that’s produced every day around the world in significant amounts.
The Introductory College Level Experience in Microbiology (iCLEM) – an immersive summer science program hosted by the Joint BioEnergy Institute – has an impressive track record of helping socioeconomically disadvantaged high schoolers pursue college education. Hoping to share the secret sauce of their instructional model, a group of former and current scientific advisors have now published the iCLEM curriculum.
Adapted from an original release published by Lawrence Livermore National Laboratory. Read the full story here Plant cell walls contain a renewable, nearly-limitless supply of sugar that can be used as a carbon source for microbe-based chemical and biofuel production. However, retrieving these sugars isn’t all that easy. Imidazolium ionic liquid (IIL) solvents are some
A new biosynthetic production pathway developed by scientists at the Joint BioEnergy Institute could provide a sustainable alternative to conventional synthetic blue dye. The highly efficient fungi-based platform may also open the door for producing many other valuable biological compounds that are currently very hard to manufacture.
Four Lawrence Berkeley National Laboratory (Berkeley Lab) scientists have been elected into the National Academy of Sciences (NAS) in recognition of their exemplary past and and continuing original research.