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To Speed Discovery, Infrared Microscopy Goes ‘Off the Grid’

Researchers from Caltech, UC Berkeley, and the Berkeley Synchrotron Infrared Structural Biology Imaging Program (BSISB) reported a more efficient way to collect “high-dimensional” infrared images – where each pixel contains rich physical and chemical information. The microscopy experiments were carried out at Berkeley Lab’s Advanced Light Source.

A COSMIC Approach to Nanoscale Science

COSMIC, a multipurpose X-ray instrument at Berkeley Lab’s Advanced Light Source, has made headway in the scientific community since its launch less than 2 years ago, with groundbreaking contributions in fields ranging from batteries to biominerals.

VIDEO: On the Line: Watching Nanoparticles Get in Shape

Berkeley Lab scientists have captured real-time, high-resolution videos of liquid structures taking shape as nanoparticles form a solid-like layer at the interface between oil and water. Their findings could help advance all-liquid robotics for targeted cancer drug delivery and other applications.

Chasing Their Tails but Getting Somewhere: Reimagining the Shape of Noise Leads to Improved Molecular Models

A Berkeley Lab intern and his mentor develop an algorithm that will extract better structures from low-quality crystallography diffraction data

Focusing in on Aquatic Microbes: Berkeley Lab Scientists Receive Grant for New Microscopy Approach

A trio of Berkeley Lab scientists has been awarded a grant by the Gordon and Betty Moore Foundation to develop a unique microscopy technology that can be used to study symbiosis in aquatic microbes – biological relationships that have a large influence on ecosystems and the planet’s climate. The grant is part of a three-year, $19-million project within the Foundation’s Symbiosis in Aquatic Systems Initiative.

New Algorithm Sharpens Focus of World’s Most Powerful Microscopes

Blurry photo? There’s a photoshop tool for that. Blurry molecular structure map? Now, there’s a tool for that too.

This Enigmatic Protein Sculpts DNA to Repair Harmful Damage

Sometimes, when something is broken, the first step to fixing it is to break it even more. Scientists have discovered this is the case for a human DNA repair protein that functions by marking and then further breaking damaged DNA. Their surprising findings have provided much-needed insight into how DNA repair works in healthy cells, as well as how different mutations can translate into different diseases and cancer.

Scientists Capture 3D Images of Nanoparticles, Atom by Atom, With Unprecedented Precision

A research team including scientists from Berkeley Lab has developed a technique that produces atomic-scale 3D images of nanoparticles tumbling in liquid between sheets of graphene, the thinnest material possible.

When Solids and Liquids Meet: In Nanoscale Detail

To better understand how a liquid interacts with the surface of a solid, Berkeley Lab researchers developed a platform to explore these interactions under real conditions at the nanoscale using a technique that combines infrared light with an atomic-scale probe.

Big Data at the Atomic Scale: New Detector Reaches New Frontier in Speed

A superfast detector installed on an electron microscope at Berkeley Lab’s Molecular Foundry will reveal atomic-scale details across a larger sample area than could be seen before, and produce movies showing chemistry in action and changes in materials.