News Center

Mapping a Cell’s Destiny

Scientists at Berkeley Lab and UC Berkeley have developed a way to spatially map gene expression data to determine a cell’s fate. The method could go far in interrogating human tissue organization and helping elucidate key aspects of development, human health and disease.

Revealing the Fluctuations of Flexible DNA in 3-D

Scientists have captured the first high-resolution 3-D images from individual double-helix DNA segments attached to gold nanoparticles, which could aid in the use of DNA segments as building blocks for molecular devices that function as nanoscale drug-delivery systems, markers for biological research, and components for electronic devices.

Scientists Discover Protein’s Starring Role in Genome Stability, and Possibly Cancer Prevention

A protein called XPG plays a previously unknown and critical role helping to maintain genome stability in human cells. It may also help prevent breast, ovarian, and other cancers associated with defective BRCA genes.

It Takes a Thief

The discovery by Berkeley Lab researchers of the structural basis by which bacteria are able to capture genetic information from viruses and other foreign invaders for use in their own immunological system holds promise for studying or correcting problems in human genomes.

A Hot Start to the Origin of Life?

Researchers from Berkeley Lab and the University of Hawaii at Manoa have shown for the first time that cosmic hot spots, such as those near stars, could be excellent environments for the creation of molecular precursors to DNA.

Unlocking the Key to Immunological Memory in Bacteria

Berkeley Lab researchers have revealed how bacteria “steal” genetic information from foreign invaders for use in their own immunological memory system.

Golden Approach to High-speed DNA Reading

Berkeley researchers have created the world’s first graphene nanopores that feature integrated optical antennas. The antennas open the door to high-speed optical nanopore sequencing of DNA.

RCas9: A Programmable RNA Editing Tool

A powerful scientific tool for editing the DNA instructions in a genome can now also be applied to RNA as Berkeley Lab researchers have demonstrated a means by which the CRISPR/Cas9 protein complex can be programmed to recognize and cleave RNA at sequence-specific target sites.

MaxBin: Automated Sorting Through Metagenomes

MaxBin is an automated software program for binning the genomes of individual microbial species from metagenomic sequences developed at the Joint BioEnergy Institute (JBEI).

Encyclopedia of How Genomes Function Gets Much Bigger

A big step in understanding the mysteries of the human genome was unveiled today in the form of three analyses that provide the most detailed comparison yet of how the genomes of the fruit fly, roundworm, and human function. The analyses will likely offer insights into how the information in the human genome regulates development, and how it is responsible for diseases.