The discovery by Berkeley Lab researchers of the structural basis by which bacteria are able to capture genetic information from viruses and other foreign invaders for use in their own immunological system holds promise for studying or correcting problems in human genomes.
Researchers from Berkeley Lab and the University of Hawaii at Manoa have shown for the first time that cosmic hot spots, such as those near stars, could be excellent environments for the creation of molecular precursors to DNA.
Berkeley Lab researchers have revealed how bacteria “steal” genetic information from foreign invaders for use in their own immunological memory system.
Berkeley researchers have created the world’s first graphene nanopores that feature integrated optical antennas. The antennas open the door to high-speed optical nanopore sequencing of DNA.
A powerful scientific tool for editing the DNA instructions in a genome can now also be applied to RNA as Berkeley Lab researchers have demonstrated a means by which the CRISPR/Cas9 protein complex can be programmed to recognize and cleave RNA at sequence-specific target sites.
MaxBin is an automated software program for binning the genomes of individual microbial species from metagenomic sequences developed at the Joint BioEnergy Institute (JBEI).
A big step in understanding the mysteries of the human genome was unveiled today in the form of three analyses that provide the most detailed comparison yet of how the genomes of the fruit fly, roundworm, and human function. The analyses will likely offer insights into how the information in the human genome regulates development, and how it is responsible for diseases.
The JBEI GT Collection, the first glycosyltransferase clone collection specifically targeted for the study of plant cell wall biosynthesis, is expected to drive basic scientific understanding of GTs and better enable the manipulation of plant cell walls for the production of biofuels and other chemical products.
Berkeley Lab researchers have shed new light on a type of molecular motor used to package the DNA of a number of viruses, including herpes and the adenoviruses. Their findings could help in the development of more effective drugs and inspire the design of new and improved synthetic biomotors.
Berkeley Lab researchers led the development of a new technique for identifying gene enhancers – sequences of DNA that act to amplify the expression of a specific gene – in the genomes of humans and other mammals. Called SIF-seq, this new technique complements existing genomic tools, such as ChIP-seq, and offers additional benefits.