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Sequencing of Green Alga Genome Provides Blueprint to Advance Clean Energy, Bioproducts

Scientists have sequenced the genome of a green alga that has drawn commercial interest as a strong producer of quality lipids for biofuel production. The chromosome-assembly genome of Chromochloris zofingiensis provides a blueprint for new discoveries in producing sustainable biofuels, antioxidants, and other valuable bioproducts.

Scientists Sequence Genome of Snail That Spreads Parasitic Worm

Scientists have characterized the genome of a freshwater snail that is instrumental in transmitting a parasitic worm to humans. The achievement could help researchers disrupt the life cycle of B. glabrata and potentially eliminate schistosomiasis, also known as snail fever.

Designing Cyclic Oligomers: Greater Than the Sum of Their Parts

-Written By Lida Gifford Cyclic proteins that assemble from multiple identical subunits (homo-oligomers) play key roles in many biological processes, including cell signaling and enzymatic catalysis and protein function. Researchers in Berkeley Lab’s Molecular Biophysics and Integrated Bioimaging (MBIB) Division worked with University of Washington’s David Baker, who led a team to design in silico

Five Berkeley Lab Scientists Among New Fellows Elected to the American Academy of Arts and Sciences

The American Academy of Arts and Sciences announced today the election of 188 fellows, five of whom are scientists at Berkeley Lab. The new Berkeley Lab fellows are Jamie Cate, Christopher Chang, Roger Falcone, Michael Witherell and Katherine Yelick. All hold joint faculty appointments at UC Berkeley.

Researchers Gain Insight into Protein Critical to Zika Virus Reproduction

Berkeley Lab researchers collaborated with colleagues from the University of Indiana and Texas A&M University to solve the atomic structure of a Zika virus protein that is key to viral reproduction. The X-ray studies were conducted at the Advanced Light Source in the Berkeley Center for Structural Biology.

Could This Enzyme Help Turn Biofuel Waste into Something Useful?

Researchers at the Joint BioEnergy Institute are looking to common soil bacteria for help in converting aryl compounds, a common waste product from biofuels synthesis, into something of value.

Cryo-Electron Microscopy Achieves Unprecedented Resolution Using New Computational Methods

Cryo-electron microscopy (cryo-EM)—which enables the visualization of viruses, proteins, and other biological structures at the molecular level—is a critical tool used to advance biochemical knowledge. Now Lawrence Berkeley National Laboratory (Berkeley Lab) researchers have extended cryo-EM’s impact further by developing a new computational algorithm that was instrumental in constructing a 3-D atomic-scale model of bacteriophage

New Machine Learning Technique Provides Translational Results

A team of scientists at Berkeley Lab has developed an unsupervised multi-scale machine learning technique that can automatically and specifically capture biomedical events or concepts directly from raw data.

What a Genome-Wide Screening Can Reveal about Cancer Survival

Berkeley Lab researchers have developed a 12-gene score tied to the odds of relapse-free breast cancer survival. The scoring system is based on an analysis of large genomic datasets and patient data, and it could eventually be developed for clinical use.

Thirdhand Smoke Affects Weight, Blood Cell Development in Mice

Berkeley Lab researchers found that the sticky residue left behind by tobacco smoke led to changes in weight and blood cell count in mice. These latest findings add to a growing body of evidence that thirdhand smoke exposure may be harmful.