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Beyond Biofuels: Berkeley Lab Facility a Catalyst for Broader Bio-based Economy

When the DOE’s Advanced Biofuels Process Development Unit (ABPDU) at Berkeley Lab commenced operations in 2012, the initial focus was on overcoming barriers to biofuel commercialization. To date, the ABPDU has entered into agreements with more than 30 partners.

NIH Awards $6.5 Million to Berkeley Lab for Augmenting Structural Biology Research Experience

The NIH has awarded $6.5 million to Berkeley Lab to integrate existing synchrotron structural biology resources to better serve researchers. The grant will establish a center based at the Lab’s Advanced Light Source (ALS) called ALS-ENABLE that will guide users through the most appropriate routes for answering their specific biological questions.

International Team Reconstructs Nanoscale Virus Features from Correlations of Scattered X-rays

As part of an international research team Berkeley Lab researchers contributed key algorithms which helped achieve a goal first proposed more than 40 years ago – using angular correlations of X-ray snapshots from non-crystalline molecules to determine the 3D structure of important biological objects.

Berkeley Lab Scientists Map Key DNA Protein Complex at Near-Atomic Resolution

Using cryo-electron microscopy (cryo-EM), Berkeley Lab scientists have obtained 3-D models of a human transcription factor at near-atomic resolutions. The protein complex is critical to gene expression and DNA repair, and could aid research in targeted drug development.

Internship Fuels a Student’s Budding Career in Science

Ever wonder what the Advanced Biofuels Process Demonstration Unit looks like from the inside? Check out Carolina Gutierrez’s Berkeley Lab Instagram Takeover, “The Day in the Life of an Intern at ABPDU,” at As a high school student in her hometown of Manteca, California, Carolina Gutierrez was a top student who excelled in advanced

Seeing More with PET Scans: Scientists Discover New Way to Label Chemical Compounds for Medical Imaging

Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development.

NIH Awards $9.3M for Further Development of PHENIX Structural Biology Software

PHENIX, a software suite launched 17 years ago at Berkeley Lab to automate the analysis of structural biology data, has received $9.3 million from the National Institutes of Health for continued development. The grant will support the use of PHENIX to build and refine models to solve three-dimensional macromolecular structures.

New Berkeley Lab Algorithms Extract 3-D Biological Structure From Limited Data

A new algorithmic framework called M-TIP helps researchers determine the molecular structure of proteins and viruses from X-ray free electron laser data, which is crucial in fields like biology and medicine.

Researchers ID New Mechanism for Keeping DNA Protein in Line

Electrostatic forces known as phosphate steering help guide the actions of an enzyme called FEN1 that is critical in DNA replication and repair, finds a new study led by Berkeley Lab researchers. The findings help explain how FEN1 distinguishes which strands of DNA to target, revealing key details about a vital process in healthy cells as well as providing new directions for cancer treatment research.

What’s On Your Skin? Archaea, That’s What

It turns out your skin is crawling with single-celled microorganisms – and they’re not just bacteria. A study by Lawrence Berkeley National Laboratory and the Medical University of Graz has found that the skin microbiome also contains archaea, a type of extreme-loving microbe, and that the amount of it varies with age.